Extended longevity at high altitude: Benefits of exposure to chronic hypoxia
نویسندگان
چکیده
منابع مشابه
Pulmonary hypertension in high-altitude chronic hypoxia: response to nifedipine.
Permanent residents at high altitude may develop excessive polycythaemia (H-Hb) and pulmonary hypertension, which often leads to cardiac failure. Inhibitors of calcium channels have been shown to reverse pulmonary hypertension in respiratory diseases and in primary pulmonary hypertension, but their efficiency has not been evaluated in high-altitude-induced pulmonary hypertension. Systolic pulmo...
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We determined whether postnatal pulmonary hypertension induced by 70% of pregnancy at high altitude (HA) persists once the offspring return to sea level and investigated pulmonary vascular mechanisms operating under these circumstances. Pregnant ewes were divided into two groups: conception, pregnancy, and delivery at low altitude (580 m, LLL) and conception at low altitude, pregnancy at HA (3,...
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Introduction: Chronic mountain sickness (CMS) represents a syndrome of secondary polycythemia along with thrombocytopenia, altered hemorheology, pulmonary and systemic hypertension, and congestive heart failure, occurring due to hypobaric hypoxia-anoxia-induced erythropoiesis reported in both native mountain residents and new climbers after prolonged stays at high and extreme a...
متن کاملDevelopmental responses to high altitude hypoxia.
From a review of published literature on developmental responses to high altitude, three major conclusions are derived. First, the small birth weight of high altitude native populations are adaptive responses to reduce the oxygen requirements, while the relative increase in the placental weight is a compromise mechanism to increase the volume and surface area €or a better oxygenation. Second, t...
متن کاملChronic exposure to carbon monoxide at high altitude: effects on mean electrical axis.
The effects of breathing CO continuously at high altitude on the mean electrical axis of the heart, hematocrit ratio and body weight were studied in laboratory rats. Laboratory rats were exposed for 6 weeks to: 100 or 500 ppm CO; 15,000 feet stimulated high altitude (SHA); or 100 or 500 ppm CO at SHA. SHA decreased body weight significantly; CO and CO-SHA interaction had no significant effect o...
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ژورنال
عنوان ژورنال: BLDE University Journal of Health Sciences
سال: 2017
ISSN: 2468-838X
DOI: 10.4103/bjhs.bjhs_7_17